<html><head><style type="text/css"><!-- DIV {margin:0px;} --></style></head><body><div style="font-family:times new roman, new york, times, serif;font-size:12pt"><DIV>Dear Luis and All:</DIV>
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<DIV>I have MR brain data with resolution 0.8*0.8*6.4 mm^3 and I used itk::CurvatureAnisotropicDiffusionImageFilter to smooth the data.</DIV>
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<DIV>I am worried the small lesion will be smoothed out.</DIV>
<DIV>Can sombody tell me whether I should pay special attention to apply this filter?</DIV>
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<DIV>And do I need to resample the data to be isotropic first? If I resampled the image to isotropic spacing by the geometry mean of (0.8 and 6.8), the anxial view looks too small.</DIV>
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<DIV>Thanks and my best regards</DIV>
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<DIV>Baoyun</DIV></div><br>
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